Archive for March, 2017

Becton Dickinson – C2 Office Renovation

Cyma Builders was selected by Becton Dickinson as their construction management partner to complete a comprehensive Master Plan renovation of two (2) sites, their corporate headquarters in Franklin Lakes, NJ and a manufacturing facility in Sparks, MD. This project was designed to be a multi-year effort to strategically renovate each facility, while strategically utilizing swing space and maintaining daily business operations throughout each campus. The end goal was to modernize the workplace by converting traditional office space to a more open, collaborative and flexible environment.

In Franklin Lakes, the initial C2 renovation (left) was chartered as a pilot to construct numerous flexible office features to assist in evaluation of those that would truly be functional for BD. The existing C2 area was 12,000 SF consisting of an antiquated conference facility.  The existing space was gutted back to an open floor plate, which included removal and infill of an existing elevator shaft. The new program consisted primarily of open office layout with sit-to-stand workstations, but also include private offices for high-level associates, conference rooms, huddle rooms, privacy rooms and hoteling space. A new employee training room was also programmed to accommodate large training sessions, and included modern fold partition flexibility to segregate the space into smaller areas. The space required upgrades of the existing HVAC distribution to accommodate the office layout, including new VAV’s/reheat coils and low pressure duct distribution and GRD’s. Power was distributed in the 1st floor plenum and cored through the 2nd floor slab to accommodate the workstation layout. A robust AV package was installed throughout all conference and collaboration space, including flat screen monitors, wireless projection systems and video conferencing capabilities. To increase mobility, unassigned workstations were deployed with lockers to accommodate those employees who chose to work from home more frequently. This portion of the project was completed on time and under budget with positive reviews from the associates who occupied the area.

DPT Labs – SVP Phase 2

Cyma Builders and Construction Managers were retained by DPT Laboratories to construct a new small volume parenteral (SVP) manufacturing suite and a new compounding suite at their Lakewood, NJ facility. The project was part of an ongoing master plan being executed at the facility that involves constructing individual SVP suites to fulfill the CDMO needs of their various clients

The 7,200 SF clean room was constructed to GMP EU classification and within the footprint of an active cGMP manufacturing facility. At the onset of the project, Cyma had to take extensive precautions to ensure the construction activities would not affect the active pharmaceutical manufacturing operations that were being conducted directly adjacent to the new suite. These precautions included clean room temporary partitions, strategic placement of negative air machines to ensure the control of dust and maintain pressure, as well as a diligent clean up effort to ensure that no dust or construction debris migrated into the plant. Cyma was also directly responsible for the flow of the contractors on site and ensuring they did not deviate from approved egress pathways. The FDA, EU, and DPT’s clients conducted several routine and surprise audits during construction without having a single observation that could be attributed to the construction team.

The overall construction included a modular clean room system for all clean room walls, ceiling and doors. This system was to be integrated into the existing adjacent suite that used the same modular system. Since the existing suite was in production 7-days a week, Cyma had to perform the tie-in to the suite during a previously scheduled bi-yearly shutdown. Cyma successfully completed five separate integration points at this shutdown, when the overall suite construction was only approximately 35% complete. Using the aforementioned clean room temporary partitions, Cyma was able to ensure that the existing suite was adequately sealed and protected while the rest of the suite was completed. The suites also had a trowel applied epoxy floor system with integral cove base.

The project had a significant amount of support infrastructure. This included two custom AHU’s, a new process and HVAC chilled water system, as well as a custom AWFI heat exchanger skid for an  AWFI sub-loop that was being installed as part of the project. These systems were also tied in to the existing systems already in service at the plant. Cyma worked with the engineering and production teams at the plant to schedule strategic shutdowns to allow the project to maintain schedule while almost completely negating the impact to production.

The infrastructure was installed on a new two story rooftop/internal mezzanine platform system that was constructed immediately above the process space. This platform  was independently supported from the existing structure. It is important to note that Cyma also worked with the design team to ensure that this platform was completely walkable and unobstructed by any of the ductwork, piping, or other utilities being installed to support the suite below.

At 60% completion, Cyma was informed that the customer purchased filling line was approximately 4 months behind schedule. This delay proved devastating to the client’s overall schedule to get the suite into active production by the end of 2016. In order to help their client achieve their goal, Cyma worked with their critical subcontractors to revise the sequence of construction to minimize this impact. This allowed almost 80% of the suite to be constructed while the filling line was being completed. Once the filling line arrived, Cyma rigged the unit into place as quickly as possible so the rest of the suite could be completed. Cyma then connected all of the relevant utilities and supported the startup of the filling line.



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