Tag: Manufacturing & Process

Cyma Builders was retained by Renaissance to fit out an existing space with a 5,500 SF suite intended to support the installation and operation of a new packaging line and provide a separate 5,500 SF shell space to be used for a second line that will be installed in the future. This project involved a significant amount of structural and MEP demolition within the footprint of the new and future packaging lines to allow for the new infrastructure required to support the line. This project needed to be closely coordinated with the client, as the site of the new packaging lines was adjacent to...

Cyma Builders completely renovated an existing pharmaceutical production space for August Bioservices, helping to facilitate their future business goals. The client purchased the facility with the intent of developing an extensive CDMO capability located in the middle of the United States. The initial step was to revamp the existing facility to enable manufacturing operations while the future buildings were being designed. This involved overhauling the mechanical and electrical systems, and installing new clean process utilities to support the filling process that was intended for the...

Cyma Builders successfully completed the GMP production suites for one of our confidential clients! The purpose of this project was to expand upon the facility’s existing GMP production spaces with four new Grade B Gene Therapy suites as well as an additional freezer room. We are proud to share that our team was not only able to accomplish the expansion successfully, but also overcome the project’s unique challenges in a seamless way. Creating an Efficient, Workable and Easily Accesible Layout One of Cyma’s initial tasks was to create an efficient and workable layout while also ensuring...

Cyma Builders and Construction Managers were retained by a confidential client to construct a new manufacturing suite with a corresponding compounding suite at their New Jersey facility. The project was commissioned to fulfill the manufacturing needs of a new client that had recently been entered into a contract to manufacture certain products. The 8,500 SF clean room was constructed to GMP EU classification and within the footprint of an active cGMP manufacturing facility. At the onset of the project, Cyma had to take extensive precautions to ensure the construction activities would not...

Lonza’s existing powder media suite required upgrades to achieve cGMP standards in order to continue manufacturing product. Improvements looking to be gained included improvement of process flow, congestion relief, crease facility capacity, Provide EU/FDA Compliant layout and environment and provide EU compliant airlocking. This project was scheduled for three phase in order to accommodate ongoing operations. Phase 1 included installation of new airlocks and high speed roll up doors to properly segregate the Powder suite. Additionally, the walls of the existing room were lined with heat...

The 7,200 SF clean room was constructed to GMP EU classification and within the footprint of an active cGMP manufacturing facility. At the onset of the project, Cyma had to take extensive precautions to ensure the construction activities would not affect the active pharmaceutical manufacturing operations that were being conducted directly adjacent to the new suite. These precautions included clean room temporary partitions, strategic placement of negative air machines to ensure the control of dust and maintain pressure, as well as a diligent clean up effort to ensure that no dust or...

Local to our west coast presence, Cyma Builders & Construction Managers completed a $500,000 Oven Room construction project for a confidential Fortune 500 Pharmaceutical firm in Vacaville, California. During this job, which consisted of 500 SQ.FT. of work and a very aggressive timeline, the client required renovation of this existing manufacturing space. The facility owned existing ovens to cure the product; however, they had been walled off to create additional space from previous renovation. The ovens were opened back up to the existing space and two new rooms were created – a new...

Cyma Builders was selected as the construction manager by this Pharmaceutical company to implement their Capacity Expansion Masterplan. The project was driven by spatial constraint of multiple programs throughout the site, including offices, warehouse and manufacturing (not pictured). The project was design to accommodate the additional needs of all three spaces within a single building addition. The overall project consisted of constructing a new 17,000 SF pre-engineered building structure to accommodate the new program, which was apportioned 3,500 SF office, 3,500 SF manufacturing and...

The Mogul #3 Installation consisted of three major areas of new construction: installation of a new production line, exterior equipment installation and interior equipment installation and infrastructure upgrades. All three areas were constructed while the existing facility remained in operation with no disruption except for an essential shutdown. A 36 hour site wide shutdown was necessary to perform load shedding from existing switchboards to newly furnished and installed switchboards to feed the new production line. The shutdown required coordination between two other tenants at the...