For this project, we transformed a warehouse into a state-of-the-art dynamic laboratory space, complete with new lab areas, mechanical mezzanines, and upgraded utilities.
The project encompassed diverse construction and renovation tasks to meet the client’s requirements. Central to the transformation was the creation of new lab spaces, including supporting facilities like restrooms and a loading dock area. Key features of the fitout included a 10,000 square foot mezzanine that required robust footings and steel dunnage. The new mezzanine was constructed to accommodate essential mechanical...
Almac Groundbreaking Ceremony
Cyma Builders, Almac, & the design partners gathered to celebrate the groundbreaking of the Almac North American Headquarters Expansion Project (Souderton, PA). This transformative initiative will enhance the existing campus by adding an impressive 113,410 square feet, increasing parking capacity, and implementing substantial site and utility infrastructure improvements.
Read Almac’s announcement of the ceremony here.
August Bioservices – Fill Suite Renovation
Cyma Builders completely renovated an existing pharmaceutical production space for August Bioservices, helping to facilitate their future business goals. The client purchased the facility with the intent of developing an extensive CDMO capability located in the middle of the United States.
The initial step was to revamp the existing facility to enable manufacturing operations while the future buildings were being designed. This involved overhauling the mechanical and electrical systems, and installing new clean process utilities to support the filling process that was intended for the...
Confidential Client – GMP Production Suites
Cyma Builders successfully completed the GMP production suites for one of our confidential clients! The purpose of this project was to expand upon the facility’s existing GMP production spaces with four new Grade B Gene Therapy suites as well as an additional freezer room.
We are proud to share that our team was not only able to accomplish the expansion successfully, but also overcome the project’s unique challenges in a seamless way.
Creating an Efficient, Workable and Easily Accesible Layout
One of Cyma’s initial tasks was to create an efficient and workable layout while also ensuring...
Cyma Builders Breaks Ground on Phase 2 of August Bioservices Expansion
Phase 2 Expansion has commenced and is off to an explosive start, both literally and figuratively! Breaking ground on this expansion took on a whole new meaning when the project team utilized explosives to blast through the existing bedrock.
All this effort will eventually lead to the foundation that will house a new aseptic manufacturing facility with the capacity to double their fill/finish capabilities.
Stay tuned for more exciting updates!
Cyma Builders Completes Charles River Projects
Cyma Builders recently completed a portfolio of projects for Charles River across their Malvern & Wayne Facilities. The portfolio consisted of a variety of laboratory, clean room and infrastructure upgrades across the two facilities. Click here to check out more details on the ISO 6 clean room!
Charles River – A36 Clean Room
Cyma Builders and Construction Managers completed a 3,800 SF cleanroom fit-out in Malvern, PA, on behalf of Charles River Labs. The project was started on November 2, 2020, during the height of the COVID pandemic and completed on March 22,2021.
The fit-out of the suite included three ISO 6 main production suites with multiple ISO 7 and ISO 8 entry and exit airlocks. The construction had multiple complexities from a technical and logistical perspective as it involved working seven days a week renovating an existing space adjacent to operational ISO 6 cleanrooms. Temporary washable partitions...
Cyma Completes Central Utility Plant Expansion
Cyma Builders has recently achieved mechanical completion on a 15,000 SF Central Utility Plant Expansion for a confidential client in Jacksonville, FL. Check out the flyover of the new facility below and read more about the project in the profile linked here.
Johnson & Johnson – Central Utility Plant Expansion
Cyma Builders was contracted to build an expansion to an existing Central Utility Plant in Jacksonville, FL. Not only did this project present technical challenges based on the complexity of the MEP systems and controls being implemented, but the COVID-19 pandemic created manpower, shipping, and fabrication issues that contributed to difficulties faced in completing this project. Those challenges were ultimately overcome, and the systems installed were tied-into production utility lines.
The building construction included a 15,000 square foot building erection with pre-tensioned,...
Confidential Client – Testing Building & Office Fit Out
Cyma Builders and Construction Managers is pleased to announce the successful completion of a major fit out project located at a new office and testing building in the Philadelphia Navy Yard. The project was started on July 22nd, 2020 during the height of the COVID pandemic and was approached in two phases.
The first phase included the fit out of 43,000 SF of office space requiring completion by November to accommodate enhanced social distancing needs for their employees. The work included general office space, private offices, a town hall / break room area, four bathrooms, and general...
Bright New Rising Stars
GREYSON MESSENGER, INTERN
My name is Greyson Messenger. I am 24 years old and a senior Construction Management student at Thomas Jefferson University East Falls in Philadelphia, PA. Since January 2021, I have been interning with Cyma Builders and assisting in project management operations on multiple projects while simultaneously being exposed to the many dimensions of construction management in a real-world setting. Prior to my internship at Cyma, I worked construction as a masonry laborer, landscaper, and commercial green roof installation in Philadelphia and the surrounding area. This...
Confidential Client – CAR-T R&D Laboratory
Cyma Builders and Construction Managers was retained by a confidential client to construct a new 12,000 SF R&D laboratory. The lab was designed to be in compliance with current BSL 2 and BSL 2+ biosafety levels to support current and future cell therapy initiatives.
As a part of the overall project, the team was tasked with demolishing an existing production space. This production space was mothballed in the early 2000’s and had not been used since. The demolition included the removal of full height (28’+) CMU partitions that were adjacent to active operations at the facility as well as...










