Cyma Builders successfully completed the GMP production suites for one of our confidential clients! The purpose of this project was to expand upon the facility’s existing GMP production spaces with four new Grade B Gene Therapy suites as well as an additional freezer room.
We are proud to share that our team was not only able to accomplish the expansion successfully, but also overcome the project’s unique challenges in a seamless way.
Creating an Efficient, Workable and Easily Accesible Layout
One of Cyma’s initial tasks was to create an efficient and workable layout while also ensuring...
Cyma Builders Breaks Ground on Phase 2 of August Bioservices Expansion
Phase 2 Expansion has commenced and is off to an explosive start, both literally and figuratively! Breaking ground on this expansion took on a whole new meaning when the project team utilized explosives to blast through the existing bedrock.
All this effort will eventually lead to the foundation that will house a new aseptic manufacturing facility with the capacity to double their fill/finish capabilities.
Stay tuned for more exciting updates!
Cyma Builders Completes Charles River Projects
Cyma Builders recently completed a portfolio of projects for Charles River across their Malvern & Wayne Facilities. The portfolio consisted of a variety of laboratory, clean room and infrastructure upgrades across the two facilities. Click here to check out more details on the ISO 6 clean room!
Charles River – A36 Clean Room
Cyma Builders and Construction Managers completed a 3,800 SF cleanroom fit-out in Malvern, PA, on behalf of Charles River Labs. The project was started on November 2, 2020, during the height of the COVID pandemic and completed on March 22,2021.
The fit-out of the suite included three ISO 6 main production suites with multiple ISO 7 and ISO 8 entry and exit airlocks. The construction had multiple complexities from a technical and logistical perspective as it involved working seven days a week renovating an existing space adjacent to operational ISO 6 cleanrooms. Temporary washable partitions...
Cyma Completes Central Utility Plant Expansion
Cyma Builders has recently achieved mechanical completion on a 15,000 SF Central Utility Plant Expansion for a confidential client in Jacksonville, FL. Check out the flyover of the new facility below and read more about the project in the profile linked here.
Johnson & Johnson – Central Utility Plant Expansion
Cyma Builders was contracted to build an expansion to an existing Central Utility Plant in Jacksonville, FL. Not only did this project present technical challenges based on the complexity of the MEP systems and controls being implemented, but the COVID-19 pandemic created manpower, shipping, and fabrication issues that contributed to difficulties faced in completing this project. Those challenges were ultimately overcome, and the systems installed were tied-into production utility lines.
The building construction included a 15,000 square foot building erection with pre-tensioned,...
Confidential Client – Testing Building & Office Fit Out
Cyma Builders and Construction Managers is pleased to announce the successful completion of a major fit out project located at a new office and testing building in the Philadelphia Navy Yard. The project was started on July 22nd, 2020 during the height of the COVID pandemic and was approached in two phases.
The first phase included the fit out of 43,000 SF of office space requiring completion by November to accommodate enhanced social distancing needs for their employees. The work included general office space, private offices, a town hall / break room area, four bathrooms, and general...
Bright New Rising Stars
GREYSON MESSENGER, INTERN
My name is Greyson Messenger. I am 24 years old and a senior Construction Management student at Thomas Jefferson University East Falls in Philadelphia, PA. Since January 2021, I have been interning with Cyma Builders and assisting in project management operations on multiple projects while simultaneously being exposed to the many dimensions of construction management in a real-world setting. Prior to my internship at Cyma, I worked construction as a masonry laborer, landscaper, and commercial green roof installation in Philadelphia and the surrounding area. This...
Confidential Client – CAR-T R&D Laboratory
Cyma Builders and Construction Managers was retained by a confidential client to construct a new 12,000 SF R&D laboratory. The lab was designed to be in compliance with current BSL 2 and BSL 2+ biosafety levels to support current and future cell therapy initiatives.
As a part of the overall project, the team was tasked with demolishing an existing production space. This production space was mothballed in the early 2000’s and had not been used since. The demolition included the removal of full height (28’+) CMU partitions that were adjacent to active operations at the facility as well as...
Cyma Creates Successful Safety Culture at Janssen PDMS Project
Cyma Builders & Construction Managers Creates Successful Safety Culture at Janssen PDMS Expansion Project
Cyma Builders and Construction Managers, in conjunction with our contractors and Janssen Pharmaceutical LLC, successfully created and fostered a proactive, effective and collaborative safety culture on this fast track project.
Janssen Pharmaceutical Research & Development LLC based in Malvern PA selected Cyma Builders to expand their footprint to an existing multi-tenant facility in Charlestown Township. Multiple tenant spaces were combined to create a new, state of the art,...
Safe and Successful Completion of a Critical Steam Shutdown
Cyma Builders & Construction Managers Announces the Safe and Successful Completion of a Critical Steam Shutdown
Cyma Builders and Construction Managers recently managed the successful completion of a critical site wide steam shutdown to replace a main steam distribution header at a large pharmaceutical research and development facility in Montgomery County, PA. This steam shutdown is part of an ongoing $3.6 million-dollar project to replace two existing 500 horsepower BTU boilers inside the Central Utility Plant. The two boilers and the associated steam header provide steam for...
Confidential Client – CAR-T Cell Therapy Lab
Cyma Builders and Construction Managers was retained by a confidential client to construct a new pilot plant at their existing PA facility. This pilot plant was designed to support a new cell therapy suite that was being designed and constructed at another facility. Due to the role of this new suite, it was imperative that it be completed and put into operation before the other facility was constructed.
The overall project consisted of the demolition of an existing suite that was renovated to accommodate the new program. The new suite included some new mechanical infrastructure while also...










