Tag: Research & Development

Cyma Builders was onboarded to execute a fast-tracked Design-Build Lab Project to support the PC&D group’s relocation from Fort Washington to Malvern. The project was highly schedule-driven to meet the business segregation deadline of Kenvue from Johnson & Johnson Innovative Medicine. A purchase order for enabling activities was received in late March 2024, with design continuing through the summer and the new M7 suite scheduled for turnover by the end of 2024. To clear the M7 Suite for construction, the Avantor group—using M7 as a storage and operational hub—had to be relocated....

For this project, we transformed a warehouse into a state-of-the-art dynamic laboratory space, complete with new lab areas, mechanical mezzanines, and upgraded utilities. The project encompassed diverse construction and renovation tasks to meet the client’s requirements. Central to the transformation was the creation of new lab spaces, including supporting facilities like restrooms and a loading dock area. Key features of the fitout included a 10,000 square foot mezzanine that required robust footings and steel dunnage. The new mezzanine was constructed to accommodate essential mechanical...

Cyma Builders and Construction Managers completed a 3,800 SF cleanroom fit-out in Malvern, PA, on behalf of Charles River Labs. The project was started on November 2, 2020, during the height of the COVID pandemic and completed on March 22,2021. The fit-out of the suite included three ISO 6 main production suites with multiple ISO 7 and ISO 8 entry and exit airlocks. The construction had multiple complexities from a technical and logistical perspective as it involved working seven days a week renovating an existing space adjacent to operational ISO 6 cleanrooms. Temporary washable partitions...

Cyma Builders and Construction Managers is pleased to announce the successful completion of a major fit out project located at a new office and testing building in the Philadelphia Navy Yard. The project was started on July 22nd, 2020 during the height of the COVID pandemic and was approached in two phases. The first phase included the fit out of 43,000 SF of office space requiring completion by November to accommodate enhanced social distancing needs for their employees. The work included general office space, private offices, a town hall / break room area, four bathrooms, and general...

Cyma Builders and Construction Managers was retained by a confidential client to construct a new 12,000 SF R&D laboratory. The lab was designed to be in compliance with current BSL 2 and BSL 2+ biosafety levels to support current and future cell therapy initiatives. As a part of the overall project, the team was tasked with demolishing an existing production space. This production space was mothballed in the early 2000’s and had not been used since. The demolition included the removal of full height (28’+) CMU partitions that were adjacent to active operations at the facility as well as...

Cyma Builders was selected as the construction manager for a programmatic effort to relocate an existing R&D facility located in Radnor, PA to Malvern, PA and Spring House, PA. The Malvern renovations consisted of a complete renovation to 35,000 SF of an existing Warehouse and Office Building to construct new Analytical Labs, Formulations Labs, API Bioreactor Suites, Wash Room Facility, API Freezer Farm, Hazardous Storage Space, Mechanical Room, and Office Space, as well as the addition of 16,500 SF of new asphalt parking lot space. Existing cryofreezer farms in the existing building...

Cyma was awarded a construction management contract to perform complete interior demolition and new fit-out of approximately 8,500 SF of new laboratory in Lexicon Pharmaceutical’s new facility. New work began with construction of a self-contained penthouse mechanical unit built to supplement (27) fume hoods. New piped gas utilities, a new DI water system, and new architectural finish package including lab grade millwork, working surfaces and fixtures were also required of this project. The construction was completed successfully on a fast-track schedule and within the project...

Cyma completed a project for Monell Chemical Senses in downtown Philadelphia at 35th and Market Streets. The project required conversion of an existing 12,500 SF office plan to a new chemistry lab on the third floor of a four story building, with occupancy on the first, second, and fourth floors. Working in downtown Philadelphia, combined with working inside an occupied building made this a challenging project to say the least, however Cyma has vast experience dealing with both difficult scenarios. Existing toilet room cores adjacent to the work area were upgraded and new MEP work included...

Cyma Builders renovated an existing R&D Facility for the Bioprocess Sciences and Purification Sciences division, which supports Centocor’s manufacturing operations including trouble-shooting, technology transfer, and development of improvements to current manufacturing methods. Much of the work took place directly adjacent to occupied space which required heavy coordination with tenants and building management in order to properly coordinate utility shut-down schedules and logistics. New installation included distribution of steam, condensate, and chilled water for HVAC, process...